Histone H3 Polyclonal Antibody, 50ul[BT-AP04088] Sampling Tubes Defects in this gene are

Defects in this gene are a cause of Pitt-Hopkins syndrome

osteoprotegerin ligand

They contain two force-producing heads formed primarily from dynein heavy chains| and stalks linking the heads to a basal domain| which contains a varying number of accessory intermediate chains

the encoded protein may be involved in membrane trafficking in non-neuronal tissues

It can interact with a subclass of nuclear hormone receptors

Histone H3 Polyclonal Antibody, 50ul[BT-AP04088] Sampling Tubes Defects in this gene areHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin