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Lamin A/C(Phospho Ser392) Polyclonal Antibody, 50ul Purification This protein may be necessary

SKU: 87973865937

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Lamin A/C(Phospho Ser392) Polyclonal Antibody, 50ul Purification This protein may be necessaryThe nuclear lamina consists of a two dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B.

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Description

This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity

Each subunit contains a heme domain and a molybdopterin-binding domain

The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus

and it prevents the assembly of the C3 and C5 convertase enzymes

which is characterized by impairments in social interaction and communication

Lamin A/C(Phospho Ser392) Polyclonal Antibody, 50ul Purification This protein may be necessaryThe nuclear lamina consists of a two dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B.

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