IFI-16 Polyclonal Antibody, 50ul Pipette Controller Transcription factor E2F4 encoded by

Transcription factor E2F4 encoded by E2F4 is a member of the E2F family of transcription factors

P2RY8 is moderately expressed in undifferentiated HL60 cells

This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors

Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region

or sudden infant death syndrome

IFI-16 Polyclonal Antibody, 50ul Pipette Controller Transcription factor E2F4 encoded byIFI16 encodes a member of the HIN 200 (hematopoietic interferon inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma 1. It modulates p53 function, and inhibits cell growth in the Ras Raf signaling pathway.