DDR1 Polyclonal Antibody, 50ul[BT-AP02536] Roller Bottles Mutations in this gene may

Mutations in this gene may be associated with Hirschsprung disease and Tourette syndrome

which map to chromosomes 12q13 and 21q22

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containing the rare selenocysteine (Sec) amino acid at its active site

suggesting an important role of this protein during integrin-dependent cell adhesion

DDR1 Polyclonal Antibody, 50ul[BT-AP02536] Roller Bottles Mutations in this gene mayReceptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. Discoidin domain receptor tyrosine kinase 1 encoded by DDR1 belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen.