SOD2 Polyclonal Antibody, 100ul[BT-AP14365] Liquid Handling 2006 [PubMed 16738315])

2006 [PubMed 16738315])

this triggers NMD to degrade mRNAs containing premature stop codons

subcellular location:Colocalizes with actin

Pseudogenes of this gene have been identified on chromosome 5

This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34

SOD2 Polyclonal Antibody, 100ul[BT-AP14365] Liquid Handling 2006 [PubMed 16738315])This gene is a member of the iron manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer.