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FTO Polyclonal Antibody, 50ul Biomatrix The encoded protein may also

SKU: 87361644009

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FTO Polyclonal Antibody, 50ul Biomatrix The encoded protein may alsoFTO is a nuclear protein of the AlkB related non haem iron and 2 oxoglutarate dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

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Description

The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein

TGFB1I1 (transforming growth factor beta 1 induced transcript 1) encodes a coactivator of the androgen receptor

motility or function

This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling)

RPL5 (ribosomal protein L5) encodes a ribosomal protein that is a component of the 60S subunit

FTO Polyclonal Antibody, 50ul Biomatrix The encoded protein may alsoFTO is a nuclear protein of the AlkB related non haem iron and 2 oxoglutarate dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

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