Rad17 Polyclonal Antibody, 50ul[BT-AP07600] Immune Repertoire Sequencing Based on studies in chicken

Based on studies in chicken and mouse

Following cleavage| the mature protein translocates to the nucleus and activates transcription by binding to the SRE1

As an oxoglutarate/malate carrier

Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis

Unleash the power of recombinant trypsin solution

Rad17 Polyclonal Antibody, 50ul[BT-AP07600] Immune Repertoire Sequencing Based on studies in chickenThe protein encoded by RAD17 (RAD17 checkpoint clamp loader component) is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint