RSPO4 Rabbit Polyclonal Antibody, 50ul Centrifuges Has no effect on basal

Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes

The deletion of one copy of this gene may be responsible for mental defects in patients with 3p- syndrome

This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha)

and spinal cord

trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR)

RSPO4 Rabbit Polyclonal Antibody, 50ul Centrifuges Has no effect on basalThis gene encodes a member of the R spondin family of proteins that share a common domain organization consisting of a signal peptide cysteine rich furin like domain thrombospondin domain and a C terminal basic region. The encoded protein may be involved in activation of Wnt beta catenin signaling pathways. Mutations in this gene are associated with anonychia congenital. Alternate splicing results in multiple transcript variants.