TH Polyclonal Antibody, 20ul[BT-AP08988] DNA Oligo Synthesis The lipid metabolic disorder sitosterolemia

The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8

It is required for recruitment of CEP110 to the centrosome

It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes

The protein encoded by IL2RB represents the beta subunit and is a type I membrane protein

Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines

TH Polyclonal Antibody, 20ul[BT-AP08988] DNA Oligo Synthesis The lipid metabolic disorder sitosterolemiaTyrosine 3 monooxygenase encoded by TH is involved in the conversion of tyrosine to dopamine. It is the rate limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have be associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.