CNTFR Polyclonal Antibody, 20ul Centrifuges EIF2AK4 encodes a member of

EIF2AK4 encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2)

The encoded enzyme specifically adds and removes nucleotides from the 3' end of small nuclear RNAs and select mRNAs and may function in controlling gene expression and cell proliferation

Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency

The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins

|tissue specificity:Expressed in a number of tissues including heart| liver and prostate

CNTFR Polyclonal Antibody, 20ul Centrifuges EIF2AK4 encodes a member ofThis gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal