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p57 (Acetyl Lys278) Polyclonal Antibody, 100ul Cell Culture Plates Alterations of F9

SKU: 86626001200

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p57 (Acetyl Lys278) Polyclonal Antibody, 100ul Cell Culture Plates Alterations of F9CDKN1C is imprinted, with preferential expression of the maternal allele. Cyclin dependent kinase inhibitor 1C is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in CDKN1C are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that CDKN1C is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for

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Description

Alterations of F9

followed by a transmembrane domain and a short C-terminal cytoplasmic tail domain

as well as the EDG family of proteins

A similar protein in mouse has been reported to play a role in liver organogenesis

separated from the transmembrane segments by a serine/threonine-rich domain

p57 (Acetyl Lys278) Polyclonal Antibody, 100ul Cell Culture Plates Alterations of F9CDKN1C is imprinted, with preferential expression of the maternal allele. Cyclin dependent kinase inhibitor 1C is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in CDKN1C are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that CDKN1C is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for

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