PIGA Polyclonal Antibody, 100ul Filtration NAV1 is similar to unc-53

NAV1 is similar to unc-53

The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature

The tandem array of 22 large| variable region exons are followed by a constant region| containing 3 exons shared by all genes in the cluster

Several isozymes of this gene family exist in vertebrates| which vary in cellular location and substrate specificity

These products include the cardiac natriuretic peptides CNP-53

PIGA Polyclonal Antibody, 100ul Filtration NAV1 is similar to unc-53This gene encodes a protein required for synthesis of N acetylglucosaminyl phosphatidylinositol (GlcNAc PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been