ING3 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation This gene is a member
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ING3 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation This gene is a memberThe protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans activated promoters, including promoters of p21 waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss
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