PEA-15 Polyclonal Antibody, 50ul[BT-AP07045] Lysosome RARs are involved in various

RARs are involved in various biological processes

with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation

This family of genes encodes multi-pass membrane proteins that are similar to both the chemokine and the transmembrane 4 superfamilies of signaling molecules

An alternatively spliced transcript variant of this gene has been reported| however| its full length nature is not known

PEA-15 Polyclonal Antibody, 50ul[BT-AP07045] Lysosome RARs are involved in variousPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.