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Phospho-5-LO (S272) Polyclonal Antibody, 100ul Cryopreservation Alternate splicing results in both

SKU: 86094258028

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Phospho-5-LO (S272) Polyclonal Antibody, 100ul Cryopreservation Alternate splicing results in bothALOX5 encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The arachidonate 5 lipoxygenasen, which is expressed specifically in bone marrow derived cells, catalyzes the conversion of arachidonic acid to 5(S) hydroperoxy 6 trans 8,11,14 cis eicosatetraenoic acid, and further to the allylic epoxide 5(S) trans 7,9 trans 11,14 cis eicosatetrenoic acid (leukotriene A4). Leukotrienes

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Description

Alternate splicing results in both coding and non-coding variants

Binds to the consensus sequence 5'-

and is inhibited by a protein in the Ras-GTPase pathway

The encoded protein catalyzes the reacylation of lysophosphatidylglycerol to phosphatidylglycerol

The protein encoded by this gene is a member of the Mastermind-like family of proteins

Phospho-5-LO (S272) Polyclonal Antibody, 100ul Cryopreservation Alternate splicing results in bothALOX5 encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The arachidonate 5 lipoxygenasen, which is expressed specifically in bone marrow derived cells, catalyzes the conversion of arachidonic acid to 5(S) hydroperoxy 6 trans 8,11,14 cis eicosatetraenoic acid, and further to the allylic epoxide 5(S) trans 7,9 trans 11,14 cis eicosatetrenoic acid (leukotriene A4). Leukotrienes

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