Mcl-1 Polyclonal Antibody, 100ul[BT-AP05274] Gene Synthesis Phosphorylation promotes association of TFEB

Phosphorylation promotes association of TFEB with 14-3-3 family proteins and retention in the cytosol

In mice| expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis

and is required for the biological activities of IL3

Scnm1 modifies phenotypic expression of Scn8a (MIM 600702) mutations (Buchner et al

This gene is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis

Mcl-1 Polyclonal Antibody, 100ul[BT-AP05274] Gene Synthesis Phosphorylation promotes association of TFEBMCL1 encodes an anti apoptotic protein, which is a member of the Bcl 2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death inducing.