Human Toll Interacting Protein, TOLLIP ELISA Kit, 96T Cell Function Analysis Isoform 3 and isoform 4

Isoform 3 and isoform 4 lack the C-terminal ligand-binding domain and may therefore constitutively activate the transcription of a specific set of genes independently of steroid hormones

Has an anti-fibrotic activity by negatively regulating the secretion of type I and type III collagens (PubMed: 28939891)

The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain

Among its related pathways are Gene Expression and Nuclear Receptor transcription pathway

The encoded protein is part of the Pol core element

Human Toll Interacting Protein, TOLLIP ELISA Kit, 96T Cell Function Analysis Isoform 3 and isoform 4