Akt Polyclonal Antibody, 50ul[BT-AP00337] Micro Centrifuge Tubes PubMed:97066971 and PubMed:9013614

PubMed:97066971 and PubMed:9013614

This gene encodes a protein that is a member of the dickkopf family

Alternatively spliced transcript variants have been described for this gene

frequently with sex reversal

Alternative splicing results in multiple transcript variants encoding differerent isoforms

Akt Polyclonal Antibody, 50ul[BT-AP00337] Micro Centrifuge Tubes PubMed:97066971 and PubMed:9013614The serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a