Lunatic Fringe Polyclonal Antibody, 20ul Peptide Modification This endoplasmic reticulum membrane protein

This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha

Multiple transcript variants encoding different isoforms have been found for BSG

A spliced antisense transcript of AVPR1B has been reported but its function is not known

The two variants are differentially expressed in embryonic tissues

The encoded enzyme (carbohydrate sulfotransferase 2) catalyzes the sulfation of a nonreducing N-acetylglucosamine residue

Lunatic Fringe Polyclonal Antibody, 20ul Peptide Modification This endoplasmic reticulum membrane proteinLFNG is a member of the fringe gene family which also includes radical and manic fringe genes. They all encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose specific beta 1,3 N acetylglucosaminyltransferase activity that leads to elongation of O linked fucose