SPAK(Phospho Ser323) Polyclonal Antibody, 50ul 3D Culture The functionality of the encoded
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SPAK(Phospho Ser323) Polyclonal Antibody, 50ul 3D Culture The functionality of the encodedThis gene encodes a serine threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation chloride coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the
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