c-Fms(Phospho Tyr809) Polyclonal Antibody, 100ul[BT-AP14521] Nucleic Acid Amplification The protein encoded by POLR1C

The protein encoded by POLR1C (RNA polymerase I subunit C) is a subunit of both RNA polymerase I and RNA polymerase III complexes

Defects in this gene are a cause of childhood cancer retinoblastoma (RB)| bladder cancer| and osteogenic sarcoma

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Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen

a constitutively expressed transcript and a cell cycle-regulated transcript

c-Fms(Phospho Tyr809) Polyclonal Antibody, 100ul[BT-AP14521] Nucleic Acid Amplification The protein encoded by POLR1CThe protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1 PDGF