ING5 Polyclonal Antibody, 20ul General Lab Use The mouse ortholog also functions

The mouse ortholog also functions in the determination of left-right asymmetry

The cytogenetic location of this locus has been reported as both 8p11 and 8q11

This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls| which implicated the role in neurodegenerative diseases

In addition| this protein interacts with and phosphorylates BRCA1| allowing BRCA1 to restore survival after DNA damage

Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G

ING5 Polyclonal Antibody, 20ul General Lab Use The mouse ortholog also functionsThis gene encodes a tumor suppressor protein that inhibits cell growth and induces apoptosis. This protein contains a PHD type zinc finger. It interacts with tumor suppressor p53 and p300, a component of the histone acetyl transferase complex, suggesting a role in transcriptional regulation. Alternative splicing and the use of multiple promoters and 3' terminal exons results in multiple transcript variants.