CD57 Polyclonal Antibody, 50ul[BT-AP02190] PCR Series IKZF3 encodes a member of

IKZF3 encodes a member of the Ikaros family of zinc-finger proteins

MCF-7 (breast adenocarcinoma)

Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators

This protein binds to the SH3 domains of GRB2| an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras)| via its C-terminal proline-rich sequences| and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2

in a block of sequence that is thought to be the result of a large X-to-Y transposition

CD57 Polyclonal Antibody, 50ul[BT-AP02190] PCR Series IKZF3 encodes a member ofCPN2 (Carboxypeptidase N Subunit 2) is a Protein Coding gene. GO annotations related to this gene include enzyme regulator activity. An important paralog of this gene is LRRTM2. he 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation. Under some circumstances it may be an allosteric modifier of the catalytic subunit.