Rat Glycogen Synthase Kinase-3 Beta, GSK3B ELISA Kit, 96T Fluorescent Staining Defects in this gene are

Defects in this gene are a cause of Wolfram syndrome 2

Induces ovarian granulosa cell apoptosis

CENPP is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al

Recognizes TERF1

Biologically important in the destruction of opioid Peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed: 2966343) (By similarity)

Rat Glycogen Synthase Kinase-3 Beta, GSK3B ELISA Kit, 96T Fluorescent Staining Defects in this gene areConstitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen Synthase (GYS1 or GYS2), EIF2B, CTNNB1 beta catenin, APC, AXIN1, DPYSL2 CRMP2, JUN, NFATC1 NFATC, MAPT TAU and MACF1. Requires primed phosphorylation of the majority of its substrates. In skeletal muscle, contributes to