IκB-alpha Polyclonal Antibody, 50ul[BT-AP10545] Gel & Buffers a POZ/zinc finger transcription repressor

a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis

Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4

are located within a 1

synaptogenesis and lymphocyte activation

MED8 encodes a protein component of the mediator complex

IκB-alpha Polyclonal Antibody, 50ul[BT-AP10545] Gel & Buffers a POZ/zinc finger transcription repressorThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell