MARH7 Polyclonal Antibody, 20ul Antibody Humanization Transcription factor involved in regulating

Transcription factor involved in regulating gene activity following the primary growth factor response

This copy of the gene is full-length and is in the telomeric duplicated region

Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence

The nuclear export signal is required for export from the nucleus and the interactions with itself and p75NTR/NGFR

This gene is highly expressed in organs involved in lipid metabolism| and may play a role in Zellweger syndrome| in which cells are deficient in peroxisomes and have impaired bile acid synthesis

MARH7 Polyclonal Antibody, 20ul Antibody Humanization Transcription factor involved in regulatingMARCH7 is a member of the MARCH family of membrane bound E3 ubiquitin ligases (EC 6. 3. 2. 19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004