MVK Polyclonal Antibody, 50ul Microplate Mixer FAM111B encodes a protein with

FAM111B encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus

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but not T-lymphocytes or nonhematopoietic cells

ADRA2B encodes a seven-pass transmembrane protein

MVK Polyclonal Antibody, 50ul Microplate Mixer FAM111B encodes a protein withMVK encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of MVK results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever