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ANGP2 Polyclonal Antibody, 50ul Organelle Studies The epitopes that elicit these

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ANGP2 Polyclonal Antibody, 50ul Organelle Studies The epitopes that elicit theseThe protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE 2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.

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Description

The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-terminal domain of the protein

a MAM domain and a C-terminal GPI-anchoring site

heme A: farnesyltransferase cytochrome c oxidase assembly factor is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane

The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen

Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases

ANGP2 Polyclonal Antibody, 50ul Organelle Studies The epitopes that elicit theseThe protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE 2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.

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