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ErbB-3 Polyclonal Antibody, 100ul[BT-AP03043] Lysosome Expression of this gene may

SKU: 84113758807

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ErbB-3 Polyclonal Antibody, 100ul[BT-AP03043] Lysosome Expression of this gene mayERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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Description

Expression of this gene may be downregulated in pancreatic cancer

HLA-DMB belongs to the HLA class II beta chain paralogues

which are important regulators of hematopoiesis and cardiogenesis in mammals

The N-end rule pathway is one proteolytic pathway of the ubiquitin system

The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distin

ErbB-3 Polyclonal Antibody, 100ul[BT-AP03043] Lysosome Expression of this gene mayERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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