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EDAR Polyclonal Antibody, 100ul Plasma This kinase can be activated

SKU: 83922106077

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USD123.75 USD170.75

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EDAR Polyclonal Antibody, 100ul Plasma This kinase can be activatedThis gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor kappaB, JNK, and caspase independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.

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Description

This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells

The encoded protein is primarily expressed in the epidermis| and plays a critical role in keratinocyte proliferation and differentiation

The encoded protein functions as a transcriptional co-regulator| and as an E3 ubiquitin ligase that promotes the ubiquitination and proteasomal degradation of target proteins

Rho-related GTP-binding protein RhoD encoded by this gene binds GTP and is a member of the small GTPase superfamily

but the full-length nature and biological activity of only two variants are determined

EDAR Polyclonal Antibody, 100ul Plasma This kinase can be activatedThis gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor kappaB, JNK, and caspase independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.

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