p53 Rabbit Polyclonal Antibody, 50ul[BT-AP11724] Contamination Detection & Removal Mutations in ACTA1 cause nemaline

Mutations in ACTA1 cause nemaline myopathy type 3

This enzyme is required for post-replicative DNA damage repair

chromosome 9 encompasses the largest interferon family gene cluster

Mutations in this gene have been associated with nephronophthisis type 2

|tissue specificity:Expressed at low levels in several tissues| including brain| kidney| lung| prostate| testis| spinal cord| adrenal gland| and trachea

p53 Rabbit Polyclonal Antibody, 50ul[BT-AP11724] Contamination Detection & Removal Mutations in ACTA1 cause nemalineThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative