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Ku-70 (Acetyl Lys317) Polyclonal Antibody, 20ul Peptide Modification The protein encoded by this

SKU: 83663613080

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Ku-70 (Acetyl Lys317) Polyclonal Antibody, 20ul Peptide Modification The protein encoded by thisThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90

The encoded protein is localized to mitochondria and may also play a neuroprotective role as a molecular chaperone

It has now been found that this gene is involved in the regulation of many NR and non-NR activities| including metabolism| adipogenesis and chromatin organization

The phosphorylation of neutrophil cytosolic factor 4 was found to negatively regulate the enzyme activity

These mutations have been shown to cause diverse changes in the pattern of DNA methylation

Ku-70 (Acetyl Lys317) Polyclonal Antibody, 20ul Peptide Modification The protein encoded by thisThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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