ILK Polyclonal Antibody, 50ul Tubes Defects in CNGB1 are a

Defects in CNGB1 are a cause of cause of retinitis pigmentosa type 45

subcellular location:In the nucleus

This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen

The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport

The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L)

ILK Polyclonal Antibody, 50ul Tubes Defects in CNGB1 are aILK encodes a protein with a kinase like domain and four ankyrin like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript