CaMKK2(Phospho-Ser511) Rabbit Polyclonal Antibody, 20ul Pathway and Network Analysis Inhibition of mTORC1 results in

Inhibition of mTORC1 results in a loss of TFEB phosphorylation

while expression is weak to moderate in astrocytomas

SHC3 (SHC (Src Homology 2 Domain Containing) Transforming Protein 3) is a Protein Coding gene

It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through eit

1998 [PubMed: 9616133])

CaMKK2(Phospho-Ser511) Rabbit Polyclonal Antibody, 20ul Pathway and Network Analysis Inhibition of mTORC1 results inThe product of this gene belongs to the Serine Threonine protein kinase family and to the Ca(2+) calmodulin dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium calmodulin dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP activated protein kinase (AMPK). This gene has its strongest expression in the brain and