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BRMS-1 Polyclonal Antibody, 100ul[BT-AP00979] Erlenmeyer Flasks The encoded protein is widely

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BRMS-1 Polyclonal Antibody, 100ul[BT-AP00979] Erlenmeyer Flasks The encoded protein is widelyBRMS1 reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. Breast cancer metastasis suppressor 1 encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different

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Description

The encoded protein is widely used as a marker for hematopoietic stem cells

PTM:Proteolytically cleaved by caspases during apoptosis

It is thought to function in neurite outgrowth and process elongation during neuronal differentiation

The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules

In skeletal muscles contraction

BRMS-1 Polyclonal Antibody, 100ul[BT-AP00979] Erlenmeyer Flasks The encoded protein is widelyBRMS1 reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. Breast cancer metastasis suppressor 1 encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different

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