BRCA2 Polyclonal Antibody, 50ul Petri Dishes including RNA polymerase II transcription

including RNA polymerase II transcription

some protein-coding and some not

It encodes a zinc finger protein that can bind to retinoblastoma protein| estrogen receptor| and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene

Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2

The protein functions as a guanine nucleotide exchange for RAB5B and RAB31

BRCA2 Polyclonal Antibody, 50ul Petri Dishes including RNA polymerase II transcriptionInherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is