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p53 Polyclonal Antibody, 100ul[BT-AP06825] Sample Library Tubes and knockout mice have been

SKU: 82960086255

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p53 Polyclonal Antibody, 100ul[BT-AP06825] Sample Library Tubes and knockout mice have beenTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

and knockout mice have been shown to develop spontaneous tumors

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p53 Polyclonal Antibody, 100ul[BT-AP06825] Sample Library Tubes and knockout mice have beenTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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