CD43 Rabbit Polyclonal Antibody, 50ul Peptide Modification It is a predominantly cytoplasmic

It is a predominantly cytoplasmic protein and is expressed in a variety of human cell lines

suggested that these transcripts are translated

It is thought to be involved in the process of myelination

Mutations in this gene cause glycogen storage disease type 14

Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells

CD43 Rabbit Polyclonal Antibody, 50ul Peptide Modification It is a predominantly cytoplasmicThe protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes T lymphocytes monocytes granulocytes and some B lymphocytes. It may be part of a physiologic ligand receptor complex involved in T cell activation. During T cell activation this protein is actively removed from the T cell APC (antigen presenting cell) contact site suggesting a negative regulatory role in adaptive immune response.