PDCD5 Polyclonal Antibody, 100ul Cell Dissociation Mutations in this gene are

Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy

aureus| and C

Belongs to the RAB6IP1 family

Homodimerization is mediated by the coiled coil domain

It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation

PDCD5 Polyclonal Antibody, 100ul Cell Dissociation Mutations in this gene areThis gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12