Raf-1 Polyclonal Antibody, 100ul[BT-AP13537] Recombinant Protein Expression 2004 [PubMed 15150103])

2004 [PubMed 15150103])

and hence neuronal excitability

DGK-epsilon shows specificity for arachidonyl-containing diacylglycerol

Polymorphisms in this gene may be associated with increased risk of arrhythmias and sudden cardiac death

with some of the isoforms being membrane-bound and others being soluble

Raf-1 Polyclonal Antibody, 100ul[BT-AP13537] Recombinant Protein Expression 2004 [PubMed 15150103])This gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.