Mcl-1 Polyclonal Antibody, 50ul[BT-AP05274] Subcellular Fractions Dok-5 and Dok-6 are more

Dok-5 and Dok-6 are more similar to each other than to the other Dok family members

Binding of the ligand inhibits cAMP accumulation

This receptor is a positive regulator of apoptosis

and is involved in calcium sequestration associated with muscular excitation and contraction

Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues

Mcl-1 Polyclonal Antibody, 50ul[BT-AP05274] Subcellular Fractions Dok-5 and Dok-6 are moreMCL1 encodes an anti apoptotic protein, which is a member of the Bcl 2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death inducing.