JAZF1 Rabbit Polyclonal Antibody, 50ul Dry Bath The LIM and SH3 protein

The LIM and SH3 protein 1 is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane

This family includes microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division

AFF1has been shown to promote the expression of CD133

653 bases and maps to human chromosome 2q14

An important paralog of this gene is ZC3H4

JAZF1 Rabbit Polyclonal Antibody, 50ul Dry Bath The LIM and SH3 proteinThis gene encodes a nuclear protein with three C2H2 type zinc fingers and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Alternatively spliced variants which encode different protein isoforms have been described; however not all variants have been fully characterized