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NPM(Phospho-Thr95) Rabbit Polyclonal Antibody, 100ul Pipette Holder Versican core protein encoded is

SKU: 81334277697

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PLN141.00 PLN169.00

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NPM(Phospho-Thr95) Rabbit Polyclonal Antibody, 100ul Pipette Holder Versican core protein encoded isThis gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified.

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Description

Versican core protein encoded is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix

Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis

also known as neuralized-like protein 4

NFIA encodes a member of the NF1 (nuclear factor 1) family of transcription factors

supporting healthy cell growth

NPM(Phospho-Thr95) Rabbit Polyclonal Antibody, 100ul Pipette Holder Versican core protein encoded isThis gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified.

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