Caspase12 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos suitable for use with most

suitable for use with most types of equipment

Alternative splicing results in multiple transcript variants encoding distinct isoforms

as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele

most notably the t (9

Alternative splicing results in at least two different transcript variants

Caspase12 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos suitable for use with mostCaspases are cysteine proteases that cleave C terminal aspartic acid residues on their substrate molecules. CASP12 is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of CASP12 mediates apoptosis in response to endoplasmic reticulum stress. However, in humans CASP12 contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals