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SPG7 Polyclonal Antibody, 100ul Tubes This gene encodes a protein

SKU: 80998666687

4.6
PLN141.00 PLN163.00

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SPG7 Polyclonal Antibody, 100ul Tubes This gene encodes a proteinThis gene encodes a mitochondrial metalloprotease protein that is a member of the AAA family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Mutations in this gene cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified.

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Description

This gene encodes a protein that contains a WD-40 domain| and is thought to be involved in diphthamide biosynthesis

The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates| including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP

5 Tube Adapter

1µm Pore Size PES Membrane

the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation

SPG7 Polyclonal Antibody, 100ul Tubes This gene encodes a proteinThis gene encodes a mitochondrial metalloprotease protein that is a member of the AAA family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Mutations in this gene cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified.

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