EGF Receptor(Phospho-Tyr1045) Rabbit Polyclonal Antibody, 50ul Shakers The mRNA of this gene

The mRNA of this gene is subject to multiple RNA editing events

Alternative splicing results in multiple transcript variants| some of which encode distinct isoforms| including a protease packaged into dense core granules (PC5A) and a type 1 membrane bound protease (PC5B)

Other variants exist

such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2)

IL-22 is a ligand for CRF2-4

EGF Receptor(Phospho-Tyr1045) Rabbit Polyclonal Antibody, 50ul Shakers The mRNA of this geneThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.