PU.1 Polyclonal Antibody, 20ul Serological Pipets Required for homologous recombination repair

Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC)

Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis

Transcripts that initiate from an upstream promoter encode alpha isoforms

Involved in autophagy in controlling protein turnover during neuronal development

Take on any genetic challenge with LightNing™ EcoRV Restriction Enzymes

PU.1 Polyclonal Antibody, 20ul Serological Pipets Required for homologous recombination repairSPI1 encodes an ETS domain transcription factor that activates gene expression during myeloid and B lymphoid cell development. The nuclear protein binds to a purine rich sequence known as the PU box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. Spi 1 proto oncogene can also regulate alternative splicing of target genes. Multiple transcript variants encoding