CDKN3 Polyclonal Antibody, 50ul[BT-AP07568] Long RNA Synthesis The amino-terminal region is protease

The amino-terminal region is protease resistant and globular in shape

May play an important role in the pathogenesis of neurogenetic diseases

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Required for localization of CDK5RAP2 to the centrosome during interphase

Non-pyrogenic

CDKN3 Polyclonal Antibody, 50ul[BT-AP07568] Long RNA Synthesis The amino-terminal region is proteaseThe protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this