AT2B3 Polyclonal Antibody, 20ul Shaker&Mixing There are two alternate translation

There are two alternate translation start codons with this gene| which result in two forms of the protein

Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis

Phosphorylation is induced by a wide range of stimuli

The protein encoded by this gene is involved in resolution of Holliday junctions| which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair

Alternative splicing of this gene generates two transcript variants

AT2B3 Polyclonal Antibody, 20ul Shaker&Mixing There are two alternate translationThe protein encoded by this gene belongs to the family of P type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate