EGF Receptor(Phospho-Tyr1068) Rabbit Polyclonal Antibody, 100ul Shakers Multiple transcription initiation sites have

Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region

Among its related pathways are RNA transport and mRNA surveillance pathway

72 kDa type IV collagenase encoded by MMP2 is a gelatinase A

The TRAF3-interacting JNK-activating modulator may also interact with a large multi-protein assembly containing the phosphatase 2A catalytic subunit

Transcript variants encoding different preproprotein isoforms have been described for this gene

EGF Receptor(Phospho-Tyr1068) Rabbit Polyclonal Antibody, 100ul Shakers Multiple transcription initiation sites haveThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.